MODELS FOR CALCULATING SOLUBILITY IN BINARY SOLVENT SYSTEMS

Citation
M. Barzegarjalali et A. Jouybangharamaleki, MODELS FOR CALCULATING SOLUBILITY IN BINARY SOLVENT SYSTEMS, International journal of pharmaceutics, 140(2), 1996, pp. 237-246
Citations number
33
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
03785173
Volume
140
Issue
2
Year of publication
1996
Pages
237 - 246
Database
ISI
SICI code
0378-5173(1996)140:2<237:MFCSIB>2.0.ZU;2-F
Abstract
Two empirical models which express the relationship between the solute solubility and the concentration of one of the solvents in a binary s olvent system are presented. The proposed models have been compared wi th previous similar models similar either in their original or modifie d forms from accuracy and predictability points of view using many exp erimental data taken from the literature. Both models were in some res pects superior to the original and modified forms of the previous mode ls. The modification of some of the previous models has improved the a ccuracy of the original models.