MODELS FOR CALCULATING SOLUBILITY IN BINARY SOLVENT SYSTEMS
Citation
M. Barzegarjalali et A. Jouybangharamaleki, MODELS FOR CALCULATING SOLUBILITY IN BINARY SOLVENT SYSTEMS, International journal of pharmaceutics, 140(2), 1996, pp. 237-246
Categorie Soggetti
Pharmacology & Pharmacy
SICI code
0378-5173(1996)140:2<237:MFCSIB>2.0.ZU;2-F
Abstract
Two empirical models which express the relationship between the solute
solubility and the concentration of one of the solvents in a binary s
olvent system are presented. The proposed models have been compared wi
th previous similar models similar either in their original or modifie
d forms from accuracy and predictability points of view using many exp
erimental data taken from the literature. Both models were in some res
pects superior to the original and modified forms of the previous mode
ls. The modification of some of the previous models has improved the a
ccuracy of the original models.