Sjogren syndrome (SS) is a common disorder in adults and involves both
glandular and extraglandular systems. We report here four cases of ch
ildhood SS complicated by chronic thyroiditis, interstitial nephritis
or sweet gland inflammation. Additionally, in one of these cases, the
central nervous system was involved. All of these complications are co
mmon in adult cases. Conclusion Childhood SS is a systemic ''ductiliti
s'' or ''exocrinopathy'' with complications which are commonly observe
d in adult cases.