TRANSIENT COMPLETE REMISSION OF ACUTE LYMPHOBLASTIC-LEUKEMIA IN RELAPSE AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION INDUCED BY DONOR LEUKOCYTE TRANSFUSIONS

Authors
DHONDT L CHATELAIN C DOYEN C OSSELAER JC FERRANT A BOSLY A
Citation
L. Dhondt et al., TRANSIENT COMPLETE REMISSION OF ACUTE LYMPHOBLASTIC-LEUKEMIA IN RELAPSE AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION INDUCED BY DONOR LEUKOCYTE TRANSFUSIONS, HEM CELL TH, 38(4), 1996, pp. 353-354
Citations number
9
Categorie Soggetti
Hematology
Journal title
HEMATOLOGY AND CELL THERAPY
ISSN journal
12693286 → ACNP
Volume
38
Issue
4
Year of publication
1996
Pages
353 - 354
Database
ISI
SICI code
1269-3286(1996)38:4<353:TCROAL>2.0.ZU;2-C
Abstract
We report the case of a young patient with refractory acute lymphoblas tic leukemia relapse, after allogeneic bone marrow transplantation, wh o was treated by donor leukocyte infusions. We observed potent adoptiv e immunotherapy which produced a cytologic complete remission and tota l chimeric state. This was of short duration and the patient died of s evere graft-versus-host disease. We present a short summary of the lit erature concerning acute lymphoblastic leukemia and donor leukocyte in fusions.