A 9-month-old infant was diagnosed as having impetigo of the central f
ace. Her clinical condition deteriorated despite treatment with intrav
enous antibiotics. Viral and bacterial cultures grew herpes simplex vi
rus type I and Staphylococcus aureus, respectively. The patient's cond
ition improved rapidly with antiviral treatment in combination with an
tibiotics. Recognition of the possibility of a combined viral and bact
erial infection is important so that adequate treatment is not delayed
.