We examined the prevalence and ages at onset of additional childhood a
nd adult psychiatric disorders in women with bulimia nervosa and evalu
ated the differential impact of a mood or anxiety disorder on the pres
entation of bulimia nervosa. One hundred fourteen women participating
in a clinical trial of cognitive-behavioral therapy for bulimia nervos
a were assessed at pretreatment with structured diagnostic methodology
. Although mood disorders were the most frequently occurring additiona
l psychiatric disorder (75%), 64% experienced an additional anxiety di
sorder. Age at onset of the anxiety disorders was markedly earlier tha
n age at onset of bulimia nervosa or other comorbid conditions. Strati
fication of the sample on the presence of a mood or anxiety disorder r
evealed no differences in the core bulimic symptoms across groups. The
presence of a mood disorder was associated with greater body dissatis
faction, lower Global Assessment of Functioning Scales (GAFS) score, m
ore externalizing disorders of childhood, and, as expected, higher Ham
ilton Depression Rating Scale (HDRS) scores. The presence of an anxiet
y disorder was related to a history of anorexia nervosa and earlier ag
e at onset of drug or alcohol dependence. Early-onset anxiety disorder
s are prevalent and may represent one potential pathway to bulimia ner
vosa. Copyright (C) 1996 by W.B. Saunders Company.