Ml. Bojin et Sa. Evans, ASYMMETRIC-SYNTHESIS OF ALPHA-AMINO PHOSPHONIC-ACIDS EMPLOYING THE CONDENSATION OF NITRONES WITH PHOSPHITE DERIVATIVES, Phosphorus, sulfur and silicon and the related elements, 111(1-4), 1996, pp. 789-789
Chiral alpha-amino phosphonic acid derivatives were synthesized by con
densing an enantiomerically homogeneous diazasilyl phosphite with a se
ries of prochiral nitrones. The reactions proceed under mild condition
s with moderate to high enantioselectivities and good yields.