AROYLATION OF 5-AMINO-2H-1,2,4-THIADIAZOLIN-3-ONES

2-Aroyl-5-aroylamino-1,2,4-thiadiazolin-3-ones (2) have been synthesiz ed through aroylation of 5-amino-2H-1,2,4-thiadiazolin-3-one(1) as an analog of cytosine. The aroylation was carried out with a substituted aroyl chloride in pyridine at 56-58 degrees C. It has been established that the intermediates of the reactions are 2-aroyl-5-amino-1,2,4-thi adiazolin-3-one (3) on the basis of the spectral data, additional expe rimental information and ab initio molecular orbital calculations.