Map. Martins et al., HALOACETYLATED ENOL ETHERS .6. SYNTHESIS OF 4,5-TRIMETHYLENE-4,5-DIHYDROISOXAZOLES, Journal of heterocyclic chemistry, 33(4), 1996, pp. 1223-1226
The investigation of the effect of the cyclopentane ring on the regioc
hemistry of the reactions of 2-acetylcyclopentanones 1a-d and beta-met
hoxyvinyl trifluoromethyl ketone derivative 2a with hydroxylamine hydr
ochloride is reported. The reactions give regio specifically the 4,5-t
rimethylene-4,5-dihydroisoxazoles 3a-d in good yields.