REACTIVITY OF ALPHA-ACYLATED BETA-ENAMINO KETONES AND ESTERS - SYNTHESIS OF PYRAZOLES

Authors
MISSIO LJ BRAIBANTE HS BRAIBANTE MEF
Citation
Lj. Missio et al., REACTIVITY OF ALPHA-ACYLATED BETA-ENAMINO KETONES AND ESTERS - SYNTHESIS OF PYRAZOLES, Journal of heterocyclic chemistry, 33(4), 1996, pp. 1243-1245
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
33
Issue
4
Year of publication
1996
Pages
1243 - 1245
Database
ISI
SICI code
0022-152X(1996)33:4<1243:ROABKA>2.0.ZU;2-R
Abstract
The reactivity of the enamino compounds 4-amino-3-phenylamino(thio)car bonyl-3-penten-2-one 1 and 2 and ethyl 3-amino-2-phenylamino(thio)carb onyl-2-butyrate 7 and 8 was studied using the reaction with hydrazine hydrate and hydrazine hydrochloride to evaluate the 1,3 electrophilic center of the compounds by the formation of the pyrazole rings. The py razoles 3, 4, 5, 9, 11 and 13 were obtained depending on the reaction conditions employed.