ASYMMETRIC-SYNTHESIS OF A LIGNAN LACTONE FROM A MESO ANHYDRIDE

Citation
Rs. Ward et al., ASYMMETRIC-SYNTHESIS OF A LIGNAN LACTONE FROM A MESO ANHYDRIDE, Tetrahedron, 52(39), 1996, pp. 12799-12814
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404020
Volume
52
Issue
39
Year of publication
1996
Pages
12799 - 12814
Database
ISI
SICI code
0040-4020(1996)52:39<12799:AOALLF>2.0.ZU;2-Z
Abstract
The synthesis of a meso-2,3-dibenzylbutanedioic acid anhydride is give n. Reaction of this with (+)-alpha-methylbenzylamine proceeds diastere oselectively to give a butanedioic acid monoamide which is converted i nto an enantiomerically enriched cis-2,3-dibenzylbutyrolactone lignan. Copyright (C) 1996 Elsevier Science Ltd