LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH ANGINA DECUBITUS

Objective. To investigate the relationship between left ventricular di astolic dysfunction and episodes of angina decubitus. Methods. The stu dy population consisted of three groups. groups I (20 controls) had no cardiovascular diseases. Group II (20 patients) had coronary artery d isease (CAD) without angina decubitus. Group III (24 cases with ejecti on fraction (EF)>45%) were selected from 26 patients with angina decub itus. Results. Left ventriculography (LVG) showed that left ventricula r (LV) first 1/3 filling fraction (1/3FF) was significantly reduced in groups III as compared with groups II and I (P<0.01). Left ventricula r end-diastolic pressure (LVEDP) significantly increased in patients w ith angina decubitus after LVG as compared with that before LVG (P<0.0 1). However, there were no statistically differences in LVEDP, before and after LVG in both groups II and I. Conclusions. Patients with angi na decubitus have abnormalities of LV diastolic filling and decrease i n LV compliance.