To evaluate the comparability of hemorheologic parameters in arterial
and venous blood, we measured hematocrit, whole blood viscosity, plasm
a viscosity, erythrocyte deformability, erythrocyte aggregation, and e
rythrocyte indices in both arterial and venous blood from 20 consecuti
ve patients scheduled for coronary artery surgery and/or valve replace
ment surgery. Hematocrit, whole blood viscosity at three shear rates (
0.05 s(-1), 0.5 s(-1), and 70 s(-1)), plasma viscosity, and erythrocyt
e aggregation factor were statistically significantly higher in venous
blood than in arterial blood, The differences may be explained by the
difference in hematocrit. Erythrocyte deformability did not differ si
gnificantly. With the availability of more precise rheological measure
ment techniques, differences such as those encountered in this study m
ay be of importance in clinical studies. It is concluded that arterial
and venous blood samples are not entirely theologically comparable.