PRELIMINARY STUDIES OF ANALGESIC AND ANTIINFLAMMATORY PROPERTIES OF CAESALPINIA-FERREA CRUDE EXTRACT

Authors
CARVALHO JCT TEIXEIRA JRM SOUZA PJC BASTOS JK DOSSANTOS D SARTI SJ
Citation
Jct. Carvalho et al., PRELIMINARY STUDIES OF ANALGESIC AND ANTIINFLAMMATORY PROPERTIES OF CAESALPINIA-FERREA CRUDE EXTRACT, Journal of ethnopharmacology, 53(3), 1996, pp. 175-178
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Journal of ethnopharmacology → ACNP
ISSN journal
03788741
Volume
53
Issue
3
Year of publication
1996
Pages
175 - 178
Database
ISI
SICI code
0378-8741(1996)53:3<175:PSOAAA>2.0.ZU;2-8
Abstract
The crude aqueous extract of the fruits of Caesalpinia ferrea Mart. (L eguminosae) has been investigated for possible anti-inflammatory and a nalgesic properties. The carrageenan induced rat hind paw edema was si gnificantly inhibited (P < 0.05) by oral administration of 300 mg/kg o f this extract. A centrally mediated analgesic effect was not observed , however, there was a dose dependent reduction in the number of total writhes induced by acetic acid.