We compared rates of DSM-III-R personality disorders in 33 first-episo
de and 26 multiple-episode bipolar patients. Patients were evaluated w
ith the patient and personality disorders versions of the Structured C
linical Interview for DSM-III-R. Significantly more multiple-episode p
atients (65%) met DSM-III-R criteria for a personality disorder than d
id first-episode patients (33%). Race was also associated with a diagn
osis of a personality disorder. Personality disorders may be associate
d with multiple affective episodes in bipolar patients.