A synthetic approach to a structurally novel series of indoline 2,2-bi
scarboxylates is employs a tandem bis-alkylation strategy to cyclize t
he indoline heteroring from the bromide 7 and diethyl bromomalonate. T
he indolines thus prepared may be N-deprotected and further functional
ized on the indoline nitrogen. Copyright (C) 1996 Elsevier Science Ltd