CYTOTOXIC ACTIVITIES OF COLOMBIAN PLANT-EXTRACTS ON CHINESE-HAMSTER LUNG FIBROBLASTS

Authors
DECERAIN AL PINZON R CALLE J MARIN A MONGE A
Citation
Al. Decerain et al., CYTOTOXIC ACTIVITIES OF COLOMBIAN PLANT-EXTRACTS ON CHINESE-HAMSTER LUNG FIBROBLASTS, PTR. Phytotherapy research, 10(5), 1996, pp. 431-432
Citations number
1
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
10
Issue
5
Year of publication
1996
Pages
431 - 432
Database
ISI
SICI code
0951-418X(1996)10:5<431:CAOCPO>2.0.ZU;2-H
Abstract
Fifty-one crude extracts from 31 Colombian plants used in traditional medicine have been screened for cytotoxicity in a MTT assay with V79 c ells. Eleven extracts (21%) were active, showing a survival percentage below 20% with respect to the controls, The most active were ethanol and dichloromethane extracts from Acnistus arborescens leaves. The IC5 0 values obtained (6 and 11 mu g/mL) encourage a more in depth investi gation.