M. Rossignol et al., EVALUATION OF THE UTILITY OF SPIROMETRY IN A REGIONAL PUBLIC-HEALTH SCREENING-PROGRAM FOR WORKERS EXPOSED TO WELDING FUMES, Journal of occupational and environmental medicine, 38(12), 1996, pp. 1259-1263
The objective of this study was to determine the usefulness of spirome
try in the screening of chronic pulmonary problems related to exposure
to welding fumes, in a regional public health-based screening program
. Pulmonary questionnaires and spirometric tests were administered twi
ce at 5-year intervals on 229 welders/cutters (mean age, 39.9 years) f
rom 31 metal manufacturing plants. The baseline mean value at the firs
t test for the forced expiratory volume in one second (FEV(1)) was 102
% of predicted, the forced vital capacity (FVC) was 107%, and the FEV(
1)/FVC ratio was 79%. The mean annual changes in the three spirometric
indicators were -47 mt, -46 mt, and -0.3%, respectively. The usefulne
ss of spirometry was assessed by looking at the relationship between e
xposure to welding fumes and changes in spirometric indices, in multiv
ariate linear regression analysis, accounting for age, height, and smo
king. A high lifetime exposure to welding fumes was associated with be
tter lung functions in the cross-sectional ap;broach (healthy worker e
ffect) but not in the longitudinal approach, where no association was
found. We concluded that the public health regional application of thi
s screening program generated too many sources of variation fm spirome
try to fulfill the objective of early detection of pulmonary function
decline related to exposure to welding fumes. Based on these observati
ons, we recommend that maintaining questionnaire screening, with spiro
metry reserved as a second-line diagnostic intervention.