PROTON MR T-2 MAPS CORRELATE WITH THE CITRATE CONCENTRATION IN THE PROSTATE

Authors
LINEY GP LOWRY M TURNBULL LW MANTON DJ KNOWLES AJ BLACKBAND SJ HORSMAN A
Citation
Gp. Liney et al., PROTON MR T-2 MAPS CORRELATE WITH THE CITRATE CONCENTRATION IN THE PROSTATE, NMR in biomedicine, 9(2), 1996, pp. 59-64
Citations number
27
Categorie Soggetti
Spectroscopy,"Radiology,Nuclear Medicine & Medical Imaging",Biophysics,"Medical Laboratory Technology
Journal title
NMR in biomedicine → ACNP
ISSN journal
09523480
Volume
9
Issue
2
Year of publication
1996
Pages
59 - 64
Database
ISI
SICI code
0952-3480(1996)9:2<59:PMTMCW>2.0.ZU;2-O
Abstract
significant correlation between water T-2 relaxation time and citrate concentration in the normal prostate is demonstrated using spatially l ocalized spectroscopy and water T,maps, These data imply that MR image s may be used to infer the concentration of citrate at high spatial re solution, Preliminary results in patients demonstrate that this relati onship is maintained in benign prostatic hyperplasia (BPH) and prostat ic carcinoma, The determination of citrate concentration and water T-2 may aid the differentiation of prostate carcinoma from BPH and normal tissue.