A 42-year-old woman presented with a web-defined pruritic erythematous
scaly plaque on the sole of each foot. The lesions, first noted about
15 years previously, were located in the medial plantar region and ex
tended laterally. Mycological study revealed infection by Scopulariops
is brevicaulis. Treatment with oral itraconazole led to temporary impr
ovement, but the symptoms returned after treatment had been stopped (p
resumably due to re-infection from ungual foci). Similar results were
subsequently obtained with oral terbinafine. S. brevicaulis is an aeti
ologic agent of onychomycosis, panophthalmia following a penetrating e
ye injury and generalized infections in immunocompromised patients, bu
t it is not considered as habitual fungal pathogen of the skin. Cutane
ous lesions caused by S. brevicaulis are very rare. Our case was resis
tant to terbinafine and itracomazole.