Despite Low Back Pain (LBP) major health impact, its nosology, etiolog
y and natural history remain ill defined in most cases. The studies of
our team explored the clinical and psychological features of non spec
ific low back pain on unselected populations of patients. Our first st
udy was conducted in a department of rheumatology. Using multivariate
satitistical methods we were able to identify three major groups of su
bjects a first group called ''purely organic'', a second group called
''purely psychiatric'', a third group with both organic and psychiatri
c features. These last two groups gathered 41 % of the subjects. An ot
her complementary study was conducted in primary care practice. Using
the General Health Questionnaire 38 % patients - a close to the above
reported percentage - were classified as having a psychological disord
er. In order to describe the natural course of acute low back pain an
inception cohort study was conducted in primary care practice. A high
rate of fast recovery was found. A critical look of the present knowle
dge on Low Back Pain shows several unsatisfactory chapters. Further st
udies on the natural history of LBP, studies on the precise etiology o
f each variety and researches on their pathophysiology are needed to c
omplete the description of nosologicaly well defined entities and to p
ave the way for relevant well designed therapeutic trials.