EFFECT OF WATER DIURESIS AND WATER RESTRICTION ON EXPRESSION OF HSPS-27, HSPS-60 AND HSPS-70 IN RAT-KIDNEY

Authors
MEDINA R CANTLEY L SPOKES K EPSTEIN FH
Citation
R. Medina et al., EFFECT OF WATER DIURESIS AND WATER RESTRICTION ON EXPRESSION OF HSPS-27, HSPS-60 AND HSPS-70 IN RAT-KIDNEY, Kidney international, 50(4), 1996, pp. 1191-1194
Citations number
18
Categorie Soggetti
Urology & Nephrology
Journal title
Kidney international → ACNP
ISSN journal
00852538
Volume
50
Issue
4
Year of publication
1996
Pages
1191 - 1194
Database
ISI
SICI code
0085-2538(1996)50:4<1191:EOWDAW>2.0.ZU;2-3
Abstract
Expression of HSP-27, HSP-60 and HSP-70 was estimated in the cortex, o uter medulla and inner medulla (papilla) of rats undergoing water diur esis or water restriction for two days. The mRNAs for HSP-27 and HSP-6 0 in renal papilla were two- to threefold greater in rats during water restriction than in those excreting a dilute urine, but levels of mRN A for HSP-70 were nor reduced by water diuresis and Western analysis f or HSP-70 protein showed no difference between water-loaded and water- restricted animals.