Pm. Olaechea et al., A PREDICTIVE MODEL FOR THE TREATMENT APPROACH TO COMMUNITY-ACQUIRED PNEUMONIA IN PATIENTS NEEDING ICU ADMISSION, Intensive care medicine, 22(12), 1996, pp. 1294-1300
Objective: To create a predictive model for the treatment approach to
community-acquired pneumonia (CAP) in patients needing Intensive Care
Unit (ICU) admission. Design: Multicenter prospective study. Setting:
Twenty-six Spanish ICUs. Patients: One hundred seven patients with CAP
, all of them with accurate etiological diagnosis, divided in three gr
oups according to their etiology in typical (bacterial pneumonia), Leg
ionella and other atypical (Mycoplasma, Chlamydia spp. and virus). For
the multivariate analysis we grouped Legionella and other atypical et
iologies in the same category. Methods: We recorded 34 variables inclu
ding clinical characteristics, risk factors and radiographic pattern.
We used a multivariate logistic regression analysis to find out a pred
ictive model. Results: We have the complete data in 70 patients. Four
variables: APACHE II, (categorized as a dummy variable) serum sodium a
nd phosphorus and ''length of symptoms'' gave an accurate predictive m
odel (c = 0.856). From the model we created a score that predicts typi
cal pneumonia with a sensitivity of 90.2% and specificity 72.4%. Concl
usion: Our model is an attempt to help in the treatment approach to CA
P in ICU patients based on a predictive model of basic clinical and la
boratory information. Further studies, including larger numbers of pat
ients, should validate and investigate the utility of this model in di
fferent clinical settings.