OBJECTIVE: We describe the clinical application and utility of high-re
solution magnetic resonance neurography (MRN) techniques to image the
normal fascicular structure of peripheral nerves and its distortion by
mass lesions or trauma in the lower extremity. METHODS: MRN images we
re obtained using a standard 1.5 Tesla magnet and custom built phased-
array coils. Patients were imaged using T1-weighted spin echo without
and with gadolinium, T2-weighted fast spin echo with fat suppression,
and short tau inversion recovery fast spin-echo pulse sequences. Nine
patients were studied, four with peripheral nerve tumors (three neurof
ibromas and one schwannoma), two with intraneural cysts, and three wit
h traumatic peripheral nerve lesions. Six patients with peripheral ner
ve mass lesions underwent surgery, thereby allowing MRN images to be c
orrelated with intraoperative and pathological findings. RESULTS: Preo
perative MRN accurately imaged the normal fascicular anatomy of periph
eral nerves and precisely depicted its relation to tumor and cystic le
sions. Increased signal on TZ-weighted fast spin-echo and short tau in
version recovery fast spin-echo pulse sequences was seen in the periph
eral nerve fascicles of patients with clinical and electrodiagnostic e
vidence of nerve injury. CONCLUSION: MRN proved useful in the preopera
tive evaluation and planning of surgery in patients with peripheral ne
rve lesions.