S. Iiyama et al., CHANGE IN ELECTRIC CHARACTERISTICS OF MEMBRANES IN RESPONSE TO TASTE STIMULI WITH INCREASING AMOUNT OF LIPIDS IN MEMBRANE MATRIX OF PVC ANDPLASTICIZER, Biophysical chemistry, 61(1), 1996, pp. 23-27
Changes in membrane electric potential in response to taste substances
were studied for membranes containing differing amounts of negatively
charged lipids in the membrane matrix of polyvinyl chloride and plast
icizer. Responses to quinine showing bitterness decreased systematical
ly with increasing the quantity of charged lipids contained in the mem
brane, whereas the response did not depend on differences in the hydro
carbon chains of lipids. The mechanism is discussed qualitatively in t
erms of hydrophobicity and hydrophilicity of the membranes.