DISTRIBUTION OF HLA DQ A1 ALLELES AND GENOTYPES IN 2 SPANISH POPULATIONS (ARAGON AND ASTURIAS)

HLA DQ A1 is probably one of the PCR-based genetic marker systems most widely used in actual forensic casework analyses. As accurate data ab out the distribution of the alleles is one of the most important prere quisites for the application in forensic biology, we studied the allel e distribution in two relevant Spanish populations (Aragonese and Astu rian). Results were in good agreement with the Hardy-Weinberg law in b oth Aragonese and Asturian populations. The power of discrimination wa s 0.92 in the Aragonese and 0.93 in Asturian sample. A test for homoge neity of the HLA DQ Al population data based on alelle frequency count s for 12 European samples was performed and no significant differences were found (P = 0.831).