TRYPANOCIDAL SESQUITERPENES FROM LYCHNOPHORA SPECIES

Authors
DEOLIVEIRA AB SAUDE DA PERRY KSP DUARTE DS RASLAN DS BOAVENTURA MAD CHIARI E
Citation
Ab. Deoliveira et al., TRYPANOCIDAL SESQUITERPENES FROM LYCHNOPHORA SPECIES, PTR. Phytotherapy research, 10(4), 1996, pp. 292-295
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
10
Issue
4
Year of publication
1996
Pages
292 - 295
Database
ISI
SICI code
0951-418X(1996)10:4<292:TSFLS>2.0.ZU;2-M
Abstract
The bioguided fractionation of the crude extracts of Lychnophora passe rina (Mart. ex DC) Gardn., L. pinaster Mart. and L. trichocarpha Spren g. led to the isolation of four compounds active against the trypomast igote forms of Trypanosoma cruzi: the sesquiterpene lactones goyazenso lide (1), eremantholide C (2), and lychnopholide (3) and a new caryoph yllene derivative, which was named lychnophoic acid (4).