GARLIC EXTRACT AND ALLICIN - BROAD-SPECTRUM ANTIBACTERIAL AGENTS EFFECTIVE AGAINST MULTIPLE-DRUG RESISTANT STRAINS OF SHIGELLA-DYSENTERIAE TYPE-1 AND SHIGELLA-FLEXNERI, ENTEROTOXIGENIC ESCHERICHIA-COLI AND VIBRIO-CHOLERAE

Authors
AHSAN M CHOWDHURY AKA ISLAM SN AHMED ZU
Citation
M. Ahsan et al., GARLIC EXTRACT AND ALLICIN - BROAD-SPECTRUM ANTIBACTERIAL AGENTS EFFECTIVE AGAINST MULTIPLE-DRUG RESISTANT STRAINS OF SHIGELLA-DYSENTERIAE TYPE-1 AND SHIGELLA-FLEXNERI, ENTEROTOXIGENIC ESCHERICHIA-COLI AND VIBRIO-CHOLERAE, PTR. Phytotherapy research, 10(4), 1996, pp. 329-331
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
10
Issue
4
Year of publication
1996
Pages
329 - 331
Database
ISI
SICI code
0951-418X(1996)10:4<329:GEAA-B>2.0.ZU;2-9
Abstract
The effects of an aqueous extract of garlic and its active constituent allicin were tested against 40 drug resistant isolates of the strains of Shigella dysenteriae type 1 and Shigella flexneri, enterotoxigenic Escherichia coli and Vibrio cholerae. The aqueous extract and allicin were shown to have potentially significant activity against all of th e bacteria tested, while of the five standard antibiotics, only gentam icin was active. Both allicin and the aqueous extract had a broad spec trum as antibacterial agents. Allicin appeared to have the strongest a ctivity compared with that of the extract and the standard antibiotics .