Objective, Prospective assessment of the accuracy of three pulse oxime
ters and two probe sites in darkly pigmented critically ill patients u
nder clinical conditions. Patients and methods. One hundred consecutiv
e, darkly pigmented critically ill adult patients with arterial lines
in situ were studied, Patients were excluded if the haemoglobin concen
tration was less than 7 g/dl and carboxyhaemoglobin or methaemoglobin
levels exceeded 2%. Pigmentation was objectively quantified with a por
table EEL reflectance spectrophotometer (Evans Electroselenium Company
, Diffusion Systems Limited, London). Reflectance was measured at nine
wavelengths, Results. The degree of pigmentation as measured by perce
ntage reflectance closely matched that of a control group of black Afr
icans from a pigmentation study, The limits of agreement (2.6% to 5.8%
), precision and bias values between pulse oximeter and co-oximeter re
adings fell within a narrow range. The 95% confidence intervals of the
limits of agreement reflected a small variation in the difference bet
ween pulse oximeter and co-oximeter readings, These small differences
were not clinically significant in the pigmented patients who were enr
olled in the study, Conclusion. The accuracy of pulse oximetry is not
adversely affected by skin pigmentation, and it remains a useful oxyge
nation monitoring device in darkly pigmented patients.