Conjunctival cytologic materials were taken from 84 eyes of postmenopa
usal and 50 eyes of premenopausal women, and specimens were graded acc
ording to the technique described by Nelson. Because the risk of conju
nctival metaplasia in postmenopausal patients was greater than in prem
enopausal patients, the cytologic gradings did not correlate with the
Schirmer's test but were found to correlate statistically with the tea
r break-up time.