Plasma cells with iron granules are rare, especially among non-alcohol
ic individuals. We report two teetotaller Chinese women with nasophary
ngeal carcinoma and non-Hodgkin's lymphoma, whose bone marrow studies
revealed plasma cells with inclusions morphologically compatible with
iron granules. The iron nature of the granules was confirmed by elemen
tal analysis. The clinical significance and the exact mechanism of for
mation of these iron inclusions in plasma cells remain unknown.