BILATERAL PRIMARY SEMINAL-VESICLE CARCINOMA

We report a rare case of bilateral primary seminal vesicle carcinoma i n a 73 yr old Australian man. To our knowledge this case report is the 48th histologically confirmed case of primary seminal vesicle neoplas ia and only the fourth reported case of primary bilateral seminal vesi cle carcinoma. Macroscopically the tumor was localized to both seminal vesicles and the adjacent right lobe of the prostate. Histologically the tumor and metastases displayed a PSA, PAP and CEA negative, well d ifferentiated papillary adenocarcinoma resembling the pattern of norma l seminal vesicle epithelium. No other primary carcinoma in the body w as demonstrated. The patient survived for 3 yrs and 4 mths without rec urrence of tumor. The pathological criteria for acceptance of primary seminal vesicle carcinoma, difficulties in clinical/radiological detec tion of seminal vesicle tumors and CA-125 immunoreactivity are discuss ed.