A study of respiratory findings was performed on 376 female workers em
ployed in a shoe manufacturing plant. The mean age of the workers was
32 years and the mean duration of their employment was 12 years. These
workers were predominantly nonsmokers. Acute and chronic respiratory
symptoms were recorded for each worker, and lung function was measured
before find after the work shift. Maximum expiratory flow-volume (MEF
V) curves were performed on which forced vital capacity (FVC), 1-secon
d forced expiratory volume (FEV(1)), and flow rates at 50% and the las
t 25% (FEF(50), FEF(25)) were measured. Significantly higher prevalenc
es of all chronic respiratory symptoms were recorded in exposed compar
ed to control workers; in particular, chest tightness (exposed: 44.7%;
control: 0%), dyspnea (exposed: 42.6%; control: 2.0%), and rhinitis (
exposed: 46.3%; control: 2.4%) were far more prevalent in workers than
in controls. Among the shoe workers, there was also a high prevalence
of acute symptoms that developed during the work shift, being most pr
onounced for nose and throat irritation (61.4%). The prevalence of acu
te and chronic respiratory symptoms increased with duration of employm
ent. Statistically significant across-shift reductions were recorded f
or all ventilation capacity tests for the group as a whole. In compari
son to predicted, the measured ventilatory capacity parameters were si
gnificantly lower for all workers (p < 0.01). Lung function abnormalit
ies increased with duration of employment. Environmental measurements
demonstrated that benzene, fur, and synthetic fibers were found at hig
her than allowable maximal concentrations (Croatian standards). The da
ta suggest that work in the shoe manufacturing industry may be respons
ible for the development of acute and chronic respiratory impairment.
(C) 1997 Wiley-Liss, Inc.