Little is known about factors that predict return to work following ca
rpal tunnel release. Patients enrolled in a prospective, community-bas
ed study of carpal tunnel syndrome in Maine were evaluated with standa
rdized questionnaires preoperatively and 6 months following carpal tun
nel release. Univariate and multivariate analyses were performed to id
entify, baseline factors associated with work disability 6 months foll
owing surgery. Thirty-one of 135 patients (23%) were out of work becau
se of CTS 6 months following surgery. The predominant preoperative var
iables associated with work absence due to CTS 6 months postoperativel
y in logistic regression analyses were Workers' Compensation, work abs
ence preoperatively, and worse mental health status (p less than or eq
ual to 0.01 for each). In analyses that considered postoperative as we
ll as preoperative variables, persistence of symptoms following surger
y was the most striking predictor of failure to return to work due to
CTS (p < 0.0001). Preoperative correlates of less complete relief of s
ymptoms in multivariate models included involvement of art attorney, m
ilder preoperative symptom severity, preoperative work absence (p < 0.
005 for each) and exposure to hand intensive work (p = 0.04). These de
lta indicate that economic and psychosocial variables have a strong in
fluence upon both return to work and the extent of symptom relief 6 mo
nths following surgery far carpal tunnel syndrome. (C) 1997 Wiley-Liss
, Inc.