A new experimental model of a vascular carrier to prefabricate a ''sec
ondary'' island flap, the popliteal musculovascular pedicle, was devel
oped in the rat. Using quantitative skin-surface fluorometry 30 minute
s after sodium fluorescein injection and a flap survival area in the p
refabricated 8 x 2.5-cm abdominal composite island flap, we compared t
he revascularization ability of our muscular carrier to nonrevasculari
zed controls: the skeletonized arteriovenous pedicle and the fasciovas
cular pedicle. The free composite graft with no vascular carrier exhib
ited near-total necrosis. The skeletonized vascular pedicle demonstrat
ed 15.2% +/- 7.8% perfusion of normal skin on dye fluorescence index m
easurements and 50% flap survival. The fasciovascular pedicle exhibite
d better revascularization, with a dye fluorescence index of 36.2 +/-
15.5 (p < 0.01) and 90% +/- 10% flap survival (p < 0.001). India ink i
njection study and histological examination of our model provided visu
al evidence of revascularization from the musculovascular pedicle, alo
ng with preservation of the carrier's muscular architecture. The muscu
lovascular pedicle is a reliable carrier for making new, vascularized
composite flaps.