NEW METHOD FOR SYNTHESIS OF SYMMETRICAL H YDROXY-BISPHOSPHONIC ESTERS

Authors
BENECH JM ELMANOUNI D LEROUX Y
Citation
Jm. Benech et al., NEW METHOD FOR SYNTHESIS OF SYMMETRICAL H YDROXY-BISPHOSPHONIC ESTERS, Phosphorus, sulfur and silicon and the related elements, 113(1-4), 1996, pp. 295-298
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
113
Issue
1-4
Year of publication
1996
Pages
295 - 298
Database
ISI
SICI code
1042-6507(1996)113:1-4<295:NMFSOS>2.0.ZU;2-Q
Abstract
A one pot synthesis Of symmetric methyl, benzyl hydroxy bisphosphonic esters can be obtained, without the use of a dialkylphosphite by intro ducing a protic reagent which removes the usual alpha-ketophosphonate step.