The title steroid derivative, 21-acetoxy-11 beta, 17 alpha-dihydroxy-3
,20-dioxopregna-1,4-dienyl 16 alpha-propionate monohydrate, C26H34O8.H
2O, crystallizes in the P6(1) space group. The hydrogen-bonded steroid
molecules, related by a hexagonal screw axis, form a cylindrical tunn
el containing a disordered water chain.