ORAL IGA-IGG TREATMENT OF CHRONIC NONSPECIFIC DIARRHEA IN INFANTS ANDCHILDREN

Authors
CASSWALL TH HAMMARSTROM L VERESS B NORD CE BOGSTEDT A BROCKSTEDT U DAHLSTROM KA
Citation
Th. Casswall et al., ORAL IGA-IGG TREATMENT OF CHRONIC NONSPECIFIC DIARRHEA IN INFANTS ANDCHILDREN, Acta paediatrica, 85(9), 1996, pp. 1126-1128
Citations number
15
Categorie Soggetti
Pediatrics
Journal title
Acta paediatrica → ACNP
ISSN journal
08035253
Volume
85
Issue
9
Year of publication
1996
Pages
1126 - 1128
Database
ISI
SICI code
0803-5253(1996)85:9<1126:OITOCN>2.0.ZU;2-Q
Abstract
The effect of orally administered immunoglobulin (IgAbulin((R))) on ch ronic non-specific diarrhoea of infancy was studied in seven children, median age 26 (21-36) months and duration of diarrhoea 32 (18-84) wee ks. Routine laboratory tests for malabsorption and small bowel biopsie s were taken in all children before and after 3 weeks of IgAbulin((R)) treatment. The biopsy specimens were analysed with regard to histopat hology, electronmicroscopy, immunohistochemistry and microbiology. The number of stools decreased from a median of 4.0 (3.0-5.0) to 1.5 (1.0 -3.5) (p < 0.05) stools per day over the study period.