A TRIS(MACROCYCLE) THAT EXHIBITS H-BOND-INDUCED BLOCKAGE OF THE CATION CHANNEL FUNCTION IN A PHOSPHOLIPID-BILAYER

Authors
MURILLO O ABEL E MAGUIRE GEM GOKEL GW
Citation
O. Murillo et al., A TRIS(MACROCYCLE) THAT EXHIBITS H-BOND-INDUCED BLOCKAGE OF THE CATION CHANNEL FUNCTION IN A PHOSPHOLIPID-BILAYER, Chemical communications, (18), 1996, pp. 2147-2148
Citations number
26
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
18
Year of publication
1996
Pages
2147 - 2148
Database
ISI
SICI code
1359-7345(1996):18<2147:ATTEHB>2.0.ZU;2-Q
Abstract
An indole-terminated tris(macrocyclic) compound, designed to be a chan nel-former, is an effective carrier in bulk membranes but fails to fun ction in a lipid bilayer owing to hydrogen bond formation which blocks the channel.