Anti-infective drugs account for between 3 and 25% of all prescription
s, between 6 and 21% of the total market value of drugs in a single co
untry, and up to 50% of the drug budget in hospitals. Not surprisingly
, in an era when cost-containment policies are at the top of the agend
a, issues related to pharmacoeconomics of antibacterial treatment have
assumed an important part in these policies. However, there are still
some misunderstandings regarding the precise terminology and differen
ce in methodology of pharmacoeconomics. The aim of this paper is to ex
plain the genealogy of pharmacoeconomics and various methods currently
used in the application of this young discipline to anti-infective tr
eatment.