HEMORHEOLOGICAL AND HEMODYNAMIC-EFFECTS OF FISH-OIL (AMEU) IN PATIENTS WITH ISCHEMIC-HEART-DISEASE AND HYPERLIPOPROTEINEMIA

Omega-3-fatty acids (n-3-FA) have various positive hemorheological eff ects in different clinical conditions. Ten male patients (mean age: 50 years) with ischemic heart disease and hyperlipoproteinemia were stud ied. They were treated by 10 capsules of Ameu (Omega Pharma, Berlin, G ermany; 0.5 g salmon oil with 33% of n-3-FA) daily for two months. Bes ides routine laboratory parameters, hemorheological measurements (whol e blood, plasma and serum viscosity) and exercise stress test with non invasive hemodynamic control at baseline and after two months of treat ment were carried out. Significant decrease (p < 0.01) of triglyceride s (58%) was found. Cholesterol and plasma viscosity showed only a mode rate decrease. Whole blood viscosity, exercise capacity and the measur ed hemodynamic parameters improved significantly (p < 0.05 or better). Our results show that this preparation can be useful in clinical prac tice because it has a beneficial effect on plasma lipids and on hemorh eological and hemodynamic parameters.