M. Pinilla et al., BIOMATERIALS IN THE RECONSTRUCTION OF THE HUMAN MIDDLE-EAR, Journal of materials science. Materials in medicine, 6(12), 1995, pp. 745-748
The use of biomaterials for reconstruction of the ossicular chain in m
iddle ear involves a different approach from that associated with othe
r regions of the organism. The features of the implantation site and t
he composition of the prosthesis are responsible for functional failur
es that result from deterioration or extrusion of the implant. Since t
he fifties, different types of materials, both biological and syntheti
c, have been employed in the attempt to achieve the ideal middle ear p
rosthesis. We present a reprospective study of 166 patients who underw
ent ossicular chain reconstruction involving autografts and homografts
of cartilage or auditory ossicle (n = 104) or synthetic prostheses (n
= 62). We compare prostheses of different compositions on the basis o
f the cases of extrusion and the histological deterioration encountere
d with each. In our experience, polymers are associated with frequent
extrusion a nd deterioration of the biomaterial, while the results a r
e better with biological implants and those made of hydroxyapatite.