HEMATOLOGICAL EFFECTS OF RADIANT HEAT-INDUCED WHOLE-BODY HYPERTHERMIAON DOGS

The effects on hematological parameters of radiant heat-induced whole body hyperthermia (WBH) at 40.5 degrees C and 41.8 degrees C were dete rmined in 6 normal dogs, Complete blood counts determined prior to WBH , immediately post WBH plateau, and at 1, 2, 7, and 14 days posttreatm ent did not change significantly following WBH at 40.5 degrees C or 41 .8 degrees C, Similarly, no significant changes were detected in plate let counts measured following 40.5 degrees C WBH, In contrast, platele t counts 11 days following 41.8 degrees C WBH increased significantly (P < 0.05) consistent with the hypothesis of induction of putative WBH -induced platelet stimulating factors.