R. Bossio et al., STUDIES ON ISOCYANIDES AND RELATED-COMPOUNDS - SYNTHESIS OF BENZO[C]-THIOPHENES BY WAY OF ACID-INDUCED 3-COMPONENT REACTIONS, Journal of the Chemical Society. Perkin transactions. I, (3), 1996, pp. 229-230
The 'diimino thioanhydrides' of cyclohex-1-ene-1,2-dicarboxylic acid h
ave been synthesized in a very simple manner by allowing 2-(arylaminot
hiocarbonyl)cyclohexanones 1 and isocyanides 3 to react in an acidic m
edium. A mechanism for this three-component reaction, based on isocyan
ide chemistry, is proposed.