METHYL HENYLPHOSPHORANYLIDENEAMINO)PYRAZINE-2-CARBOXYLATE - SYNTHESIS, CRYSTAL-STRUCTURE AND USE IN PTERIDIN-4(3H)-ONES SYNTHESIS

Authors
OKAWA T EGUCHI S KAKEHI A
Citation
T. Okawa et al., METHYL HENYLPHOSPHORANYLIDENEAMINO)PYRAZINE-2-CARBOXYLATE - SYNTHESIS, CRYSTAL-STRUCTURE AND USE IN PTERIDIN-4(3H)-ONES SYNTHESIS, Journal of the Chemical Society. Perkin transactions. I, (3), 1996, pp. 247-254
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
3
Year of publication
1996
Pages
247 - 254
Database
ISI
SICI code
0300-922X(1996):3<247:MH-S>2.0.ZU;2-C
Abstract
The title iminophosphorane 6 has been prepared from methyl 3-aminopyra zine-2-carboxylate 1 by a modified Kirsanov method using a triphenylph osphine-hexachloroethane-triethylamine system. The crystal structure o f 6 illustrated an iminophosphorane function (N=P bond). 2,3-Disubstit uted pteridin-4(3H)-ones were obtained in a one-pot reaction of 6 with isocyanates, followed by heterocyclization on addition of alcohols or amines.