BACKGROUND: Phototherapeutic keratectomy (PTK) is effective in the tre
atment of many superficial corneal disorders. The incidence of bacteri
al keratitis following PTK has not been assessed in a large, prospecti
ve clinical trial. METHODS: We report three cases of bacterial keratit
is that occurred in a prospective study of 258 consecutive PTK procedu
res at King Khaled Eye Specialist Hospital. RESULTS: Three (1.2%) of 2
58 eyes developed bacterial keratitis during a period of follow up ran
ging from 1 to 24 months. All three cases were in 183 eyes (1.6%) with
a diagnosis of climatic droplet keratopathy, while no cases were obse
rved in 75 eyes with other anterior corneal disorders. Gram-positive s
pecies (Streptococcus pneumonia in two, coagulase-negative Staphylococ
cus in one) were the predominant species isolated from all three cases
. Two of the cases were polybacterial. The final visual outcomes range
d from 20/125 to 20/400. CONCLUSIONS: The risk. of bacterial keratitis
following treatment of superficial corneal disorders with PTK is low
but its occurrence may adversely affect the final visual outcome.