THE EFFECT OF SURFACE-ACTIVE ADDITIVES ON THE PARTITIONING OF PROTEINS AND ENZYMES IN AQUEOUS 2-PHASE SYSTEMS

Authors
GAIKAR VG BODHANKAR SS LATHA V
Citation
Vg. Gaikar et al., THE EFFECT OF SURFACE-ACTIVE ADDITIVES ON THE PARTITIONING OF PROTEINS AND ENZYMES IN AQUEOUS 2-PHASE SYSTEMS, Journal of chemical technology and biotechnology, 67(4), 1996, pp. 329-332
Citations number
8
Categorie Soggetti
Engineering, Chemical",Chemistry,"Biothechnology & Applied Migrobiology
Journal title
Journal of chemical technology and biotechnology → ACNP
ISSN journal
02682575
Volume
67
Issue
4
Year of publication
1996
Pages
329 - 332
Database
ISI
SICI code
0268-2575(1996)67:4<329:TEOSAO>2.0.ZU;2-#
Abstract
The effect of cationic and anionic surface active additives on the par titioning of proteins has been studied. The surface active agents inte ract with proteins electrostatically and also hydrophobically. The inc reased hydrophobicity of the proteins because of association with surf actants is responsible for the changes in the partition coefficients a nd in some cases for precipitation of the proteins. Specific interacti ons also exist between mildly surface active amino acids and proteins.