BENZODIAZEPINE ANALOGS .11. A KINETIC-MECHANISTIC STUDY OF THE FORMATION OF 1,5-BENZODIOXEPIN-2-ONES VIA BAEYER-VILLIGER OXIDATION OF FLAVANONES

Authors
GELEBE AC KAYE PT
Citation
Ac. Gelebe et Pt. Kaye, BENZODIAZEPINE ANALOGS .11. A KINETIC-MECHANISTIC STUDY OF THE FORMATION OF 1,5-BENZODIOXEPIN-2-ONES VIA BAEYER-VILLIGER OXIDATION OF FLAVANONES, Journal of chemical research. Synopses, (1), 1996, pp. 26-27
Citations number
18
Categorie Soggetti
Chemistry
Journal title
Journal of chemical research. Synopses → ACNP
ISSN journal
03082342
Issue
1
Year of publication
1996
Pages
26 - 27
Database
ISI
SICI code
0308-2342(1996):1<26:BA.AKS>2.0.ZU;2-J
Abstract
The regioselective Baeyer-Villiger rearrangement of selected flavanone s to 1,5-benzodioxepin-2-ones, using m-chloroperbenzoic acid in CD2Cl2 , has been monitored by H-1 NMR spectroscopy: substituent effects on t he magnitude of the second-order rate constant and the regioselectivit y of heteroatom insertion have been examined.