MANDIBULAR LYMPHOMAS WITH SCLEROSIS

Two cases of non-Hodgkin's lymphoma that show a sarcomatoid pattern wi thin the jaw are described. Their primary origin in bone was demonstra ted by radiologic studies. In one case,diagnosis was delayed because t he clinical picture suggested inflammatory periodontal disease. In bot h cases, the histologic picture was similar to that of a sarcomatoid n eoplasm with intense stromal sclerosis; hemimandibulectomy was perform ed in one case. The tumor contained cells with large, irregular, somet imes lobulated nuclei and high mitotic activity, and perforated mandib ular bone with infiltration into adjacent soft tissues. The lymphoid n ature of these neoplasms was demonstrated by immunohistochemical and u ltrastructural study.