Gg. Corbucci et al., BIOCHEMICAL AND BIOMOLECULAR ASPECTS OF OXIDATIVE STRESS DUE TO ACUTEAND SEVERE HYPOXIA IN HUMAN MUSCLE-TISSUE, International journal on tissue reactions, 17(3), 1995, pp. 125-127
Mitochondrial oxidative stress was investigated in severe and acute hy
poxia and in reperfusion applied to human muscle tissues. The biochemi
cal and biomolecular relationship between the response of The respirat
ory-chain enzymic complexes and the metabolism of specific hypoxia str
ess proteins (HSP) suggest an adaptive mechanism which antagonizes the
oxidative damage due to acute and severe tissue hypoxia.