Background. Reconstruction of facial bone fractures complicated by fro
ntal sinus destruction must seal off the cranial cavity from the upper
respiratory tract to avoid ascending infections of the intracranial c
ontents. Methods. We used a bipedicled galeopericranial flap for recon
struction of the extradural and subcutaneous spaces of the frontal reg
ion, which were infected with methicillin-resistant Staphylococcus aur
eus (MRSA) following unsuccessful coverage of the anterior cranial bas
e with an anteriorly based pericranial flap. Results. The patient heal
ed uneventfully without infection. Conclusion. Because a bipedicled ga
leopericranial flap has abundant blood supply, it can be used to cover
a wide segment of the anterior cranial base. This is the first report
of the application of a bipedicled galeopericranial flap for wide rec
onstruction of the anterior cranial base.